Cognitive performance of opioid maintenance vs. abstinence

November 16, 2012February 28, 2022 ~ Jason Schwartz ~ 4 Comments

A new study finds lower cognitive functioning in maintenance patients compared with abstinent former users. It also found no difference between methadone patients and buprenorphine patients. Background To compare the cognitive performances of maintenance patients (MAIN), abstinent ex-users (ABST) and healthy non-heroin using controls (CON). Methods Case control study of 125 MAIN (94 … Continue reading Cognitive performance of opioid maintenance vs. abstinence

Methadone’s cognitive effects

August 19, 2012February 28, 2022 ~ Jason Schwartz ~ 6 Comments

Another study on methadone's cognitive effects: In one study, on the day after the last exposure to methadone, there was a significant reduction (around 70 per cent) in the level of a signal molecule which is important in learning and memory, in both the hippocampus and in the frontal area of the brain. This … Continue reading Methadone’s cognitive effects