What happened to the “crack babies”?

    Dirk Hansen reports the good news about "crack babies":   In a paper authored by Hurt, Laura M Betancourt, and others, the investigators write: “It is now well established that gestational cocaine exposure has not produced the profound deficits anticipated in the 1980s and 1990s, with children described variably as joyless, microcephalic, or unmanageable.” The authors do … Continue reading What happened to the “crack babies”?

24 month outcomes

  Another study supports the effects of twelve step participation over 24 months. (I know the abstract says "self help", but the pay-walled article makes it clear that they were looking at twelve step participation.) Abstract The goal was to identify factors that predicted sustained cocaine abstinence and transitions from cocaine use to abstinence over … Continue reading 24 month outcomes

They’ve got hope for something. But, what?

Stimulant maintenance therapy did not work 🙁 This study did not find a significant main effect of modafinil on the rate or duration of cocaine use among cocaine-dependent patients. Now they decide to polish the turd: Although these results are disappointing, we did find that modafinil-treated patients had nonsignificantly higher odds of attaining abstinence across … Continue reading They’ve got hope for something. But, what?


Published in a prestigious journal with an 'n' of 8. Unbelievable. Participants  Eight cocaine-using adults. Measurements  Subjects completed nine experimental sessions in which they were pre-treated with 0, 100 or 200 mg oral immediate release bupropion. Ninety minutes later they sampled an intranasal cocaine dose [4 (placebo), 15 or 45 mg] and made six choices between that dose and … Continue reading n=8