Another study on methadone's cognitive effects: In one study, on the day after the last exposure to methadone, there was a significant reduction (around 70 per cent) in the level of a signal molecule which is important in learning and memory, in both the hippocampus and in the frontal area of the brain. This … Continue reading Methadone’s cognitive effects
Category: Policy
We’re not alone
Pat Deegan linked to a report on the state of treatment for schizophrenia for medicaid recipients. Although there was some state-to-state variation in the findings, the study found that, while more than 90 percent of beneficiaries with schizophrenia or bipolar disorder received an evidence-based medication during the year, only 61 percent of those beneficiaries continuously … Continue reading We’re not alone
Following the evidence
Ouch: Abstract: This paper raises the question about whether the data on the medications we call antidepressants justify the label of antidepressant. The authors argue that a true antidepressant should be clearly superior to placebo, should offer a risk/benefit balance that exceeds that of alternative treatments, should not increase suicidality, should not increase anxiety and … Continue reading Following the evidence
Sentences to ponder
On drug policy reform: "Demonstrating that the frying-pan is hot does not prove that it would be prudent to leap into the fire." --Keith Humphreys
GlaxoSmithKline’s corruption
The details are simultaneously exactly what you'd expect and shocking. And some people wonder why we're reluctant to embrace the latest and greatest pharmacological fad. Keep all of this in mind next time someone suggests that medicalizing addiction treatment will improve professionalism, ethics and reliance on scientific evidence. Sham advisory boards: Glaxo also used sham … Continue reading GlaxoSmithKline’s corruption
“Disease” and recovery
“Once I became my diagnosis, there was no one left to recover.” Yesterday's Pat Deegan post led me to Dr. Daniel Fisher's work on mental illness recovery. He promotes an "empowerment" model of recovery that he contrasts with a "rehabilitation" model of recovery. According to this vision, one is capable of recovering from the mental … Continue reading “Disease” and recovery
Deconstructing “it works”
Healthcare, etc. has a great post deconstructing what it means to say a treatment works: What exactly does it mean when we say that a treatment works? Do we mean the same thing for all treatments? Are there different ways of assessing whether and how well a treatment works? I am sure you've guessed that … Continue reading Deconstructing “it works”
Intellect no shelter from cognitive bias
In a recent post I shared my observation that, as the usefulness of many psychotropics have been cast into doubt by a growing body of evidence, many people who used to chide questioners to "follow the evidence" now resort to anecdotes to defend their advocacy for these drugs. (And, denigration of other methods.) One story … Continue reading Intellect no shelter from cognitive bias
The political left and prohibition
Andrew Sullivan picks up on Jack Meserve's discussion of the political left and prohibition: Meserve: Think of a few of the currently illegal vices: recreational drug use, gambling, prostitution. With some exceptions, the left has been in favor of legalization or decriminalization of these activities. Now think of legal vices: gluttony, cigarette smoking, alcohol use. … Continue reading The political left and prohibition
The truth is dangerous
How hard is it for the DEA to have an honest conversation about drugs? Below is testimony from the director. Note the incoherence. “Is crack worse for a person than marijuana?” Polis asked Leonhart. “I believe all illegal drugs are bad,” Leonhart answered. Polis continued, asking whether methamphetamines and heroin were worse for a person's … Continue reading The truth is dangerous
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