
“For patients presenting to initiate treatment, the on-ramping/off-ramping process with MOUD mattered more than the impact of treatment choice on mortality or side effects.”
Muthulingam, D., Hassett, T. C., Madden, L. M., Bromberg, D. J., Fraenkel, L., & Altice, F. L. (2023). Preferences in medications for patients seeking treatment for opioid use disorder: A conjoint analysis. Journal of substance use and addiction treatment, 154, 209138. https://doi.org/10.1016/j.josat.2023.209138
Impact on mortality ranked 4 out of 5 in relative importance for treatment attributes for people seeking treatment for Opioid Use Disorder. (see table below) Not only was it 4th, it was far behind on-ramping and off-ramping.
- If treatment seekers rank mortality that low, how salient is mortality in non-treatment-seeking populations?
- What are the implications for public health and treatment efforts with this population?
- How might this vary by problem severity and complexity?
- Does this imply that their highest priorities are ameliorating suffering and avoiding iatrogenic suffering?
- What does this say about their relationship with opioids? What are the public health and treatment implications of that relationship?

